Ti2-E microscope with TIRF adapter, software, and component parts

The National Institute on Neurological Disorders and Stroke (NINDS) is a part of the National Institutes of Health (NIH) and conducts research into the causes, treatment, and prevention of neurological disorders and stroke. The NINDS Cell Biology and Biophysics unit (CBBU) performs measurements of microtubules and microtubule associated proteins and their kinetics and dynamics at the single molecule level. To discern the molecular level events, images of the microtubules are required in a label free manner while observing the interacting proteins with fluorescent tags. Therefore NINDS requires a brand name or equal Ti2-E microscope with TIRF adapter, TIRF objective, Elements Control Software, LED light source, XY Stage and a Fusion BT camera to replace a system that was damaged in a recent flood. The acquisition of this brand name or equal system and component parts are in necessary in order for the CBBU to perform IRM and simultaneous fluorescence measurement on microtubules and microtubule associated-protein (MAP)s.