Smart Non-invasive Assays of Physiology (SNAP)

The Smart Non-invasive Assays of Physiology (SNAP) program aims to develop a portable, multi-omic, multiplexed sensor prototype capable of implementing models that assess warfighter physiological states based on molecular biomarkers. SNAP will be rapidly adaptable to diverse DoD end user needs for readiness assessment and training, providing warfighters with a personalized view into their performance state. Recent research demonstrates that bodily fluids such as saliva carry signatures of physiological states in both health and disease, and in particular, physical and cognitive exertion. Ultimately, models of readiness or other physiological states will require point-of-person tools to process samples, analyze different classes of biomarkers in a single device, and implement these predictive models in real-world settings and on operationally relevant time frames.