MEX-AD:Clinical, epidemiological, & genetic characterization of Alzheimer's patients in the admixed Mexican population
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General Information
- Contract Opportunity Type: Solicitation (Updated)
- Updated Published Date: Jan 12, 2024 04:03 pm EST
- Original Published Date: Jan 12, 2024 02:50 pm EST
- Updated Date Offers Due: Feb 26, 2024 11:00 am EST
- Original Date Offers Due: Feb 26, 2024 11:00 am EST
- Inactive Policy: 15 days after date offers due
- Updated Inactive Date: Mar 12, 2024
- Original Inactive Date: Mar 12, 2024
- Initiative:
- None
Classification
- Original Set Aside:
- Product Service Code: AN41 - HEALTH R&D SERVICES; HEALTH CARE - OTHER; BASIC RESEARCH
- NAICS Code:
- 541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Place of Performance: MEX
Description
The purpose of this requirement is to establish a multicentre cohort study in Mexico and characterize Alzheimer's
disease (AD) patients' clinical, genetic, and phenotypic diversity in the admixed Mexican population, a group with
unique genetic admixture and environmental exposures that is underrepresented in AD research.
First, the Contractor shall determine the genetic substructure and familial contributions to AD in Mexico. This will
advance efforts to treat AD in patients with rare mutations.
Second, by assembling this large cohort, the Contractor shall work to establish a preliminary Mexican-specific
polygenic risk score (PRS) for predicting AD risk in future samples.
Please see attached RFP titled "75N95024R00016 Solicitation" for the full solicitation.
Attachments/Links
Contact Information
Contracting Office Address
- c/o 3WFN MSC 6012 301 N Stonestreet Ave
- Bethesda , MD 20892
- USA
Primary Point of Contact
- Hashim Dasti
- hashim.dasti@nih.gov
- Phone Number 3014028225
Secondary Point of Contact
- Karen Mahon
- karen.mahon@nih.gov
- Phone Number 3014357479
History
- Mar 12, 2024 11:55 pm EDTSolicitation (Updated)
- Jan 12, 2024 04:03 pm ESTSolicitation (Updated)
- Jan 12, 2024 02:50 pm ESTSolicitation (Original)